Information for scientists
Heinz Nixdorf Recall Study and Heinz Nixdorf
Multigenerational Study
Cardiovascular diseases continue to be the leading cause of death in Germany. Acute myocardial infarction requires special attention because it often cannot be treated appropriately due to its unpredictability and thus often leads to death. This makes it all the more important to intervene preventively and reduce the risk of infarction in advance. The condition for this is an improvement in early detection in people who are actually at high risk. The Heinz Nixdorf Recall Study was launched more than 20 years ago to prove that modern imaging methods allow better prediction of heart attack risk than conventional methods based on risk factors (Schmermund et al. Assessment of clinically silent atherosclerotic disease and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: rationale and design of the Heinz Nixdorf RECALL Study. Risk Factors, Evaluation of Coronary Calcium and Lifestyle. American heart journal. 2002;144(2):212-8). In 2000, random samples of people aged 45 to 74 were drawn from the population registration offices of the cities of Bochum, Essen and Mülheim. From 2000 to 2003 (HNR-T0), a total of 4814 participants (recruitment rate 55.8%) were examined in the specially established „Heinz Nixdorf Study Center“ (Stang et al. Baseline recruitment and analyses of nonresponse of the Heinz Nixdorf Recall Study: identifiability of phone numbers as the major determinant of response. European journal of epidemiology. 2005;20(6):489-96). In addition to interview and questionnaires as well as a series of medical examinations, a large number of biosamples were collected. Contact with the subjects is maintained on an ongoing basis, two follow-up examinations, 5 and 10 years after baseline (HNR-T1 and HNR-T2), have already taken place and questionnaires on current health are sent to the participants annually.
The successful work in the Heinz Nixdorf Recall Study motivated us to devote ourselves more intensively to the question of heredity and genetics of coronary vascular calcification and thus atherosclerosis. This led to the idea of continuing the study in the form of the Heinz Nixdorf Multigenerational Study (MGS), which started in 2013 (MGS-T0). In this study, 2898 spouses and children of the first generation of the test subjects were and are being examined according to the proven study protocol of the Heinz Nixdorf Recall Study in order to be able to research the development of heart disease in families. Currently, the first follow-up examination (MGS-T1) is taking place and questionnaires on current health are sent to the participants annually.
Project management: | PD Dr. B. Schmidt, Prof. Dr. A. Stang |
Funding: | Heinz Nixdorf Foundation |
Implementation: | U. Slomiany, M. Deckert, Dr. N. Sonuc |
Duration: | ongoing |
Contact: | Recall@uk-essen.de |
Data overview
Data preparation status
The data from
- HNR T0 are fully available
- HNR T1 are fully available
- HNR T2 are fully available
- MGS T0 are fully available
- MGS T1 are available end of 2023
Are you a scientist? Would you like to apply for data of our two studies? Here you will find important information.
Due to data security reasons (i.e., data contain potentially participant identifying information), the Heinz Nixdorf Recall Study and Heinz Nixdorf Multigenerational Study study do not allow sharing data as a public use file, but data requests can be addressed to recall@uk-essen.de.
Selected publications
- Jockwitz C, Krämer C, Dellani P, Caspers S. (2023) „Differential predictability of cognitive profiles from brain structure in older males and females. Geroscience“. 2023 Sep 21. Epub ahead of print. PMID: 37730943.
- Ogurtsova K, Soppa VJ, Weimar C, Jöckel KH, Jokisch M, Hoffmann B. (2023) „Association of long-term air pollution and ambient noise with cognitive decline in the Heinz Nixdorf Recall study. Environ Pollut. 15;331(Pt 1):121898.PMID: 37244536.
- Mavarani L, Albayrak-Rena S, Potthoff A, Hower M, Dolff S, Sammet S, Maischack F, Schadendorf D, Schmidt B, Esser S; (2023) „HIV HEART AGING Study. Changes in body mass index, weight, and waist-to-hip ratio over five years in HIV-positive individuals in the HIV Heart Aging Study compared to the general population. Infection.“ 1081-1091. PMID: 36930373; PMCID: PMC10352154.
- Krämer C, Stumme J, da Costa Campos L, Dellani P, Rubbert C, Caspers J, Caspers S, Jockwitz C. (2023) „Prediction of cognitive performance differences in older age from multimodal neuroimaging data.“ Geroscience. Epub ahead of print. PMID: 37308769.
- Schramm S, Krizanovic N, Roggenbuck U, Jöckel KH, Herring A, Keyvani K, Jokisch M. (2023) „Blood Kallikrein-8 and Non-Amnestic Mild Cognitive Impairment: An Exploratory Study.“ J Alzheimers Dis Rep. 2023 May 327-337 PMID: 37220622; PMCID: PMC10200235.
- Gronewold J, Jokisch M, Schramm S, Himpfen H, Ginster T, Tenhagen I, Doeppner TR, Jockwitz C, Miller T, Lehmann N, Moebus S, Jöckel KH, Erbel R, Caspers S, Hermann DM; Heinz Nixdorf Recall Study Investigative Group. (2023) „Association of regional white matter hyperintensities with hypertension and cognition in the population-based 1000BRAINS study.“ Eur J Neurol. 1174-1190. 22. PMID: 36702775.
- Gronewold J, Jokisch M, Schramm S, Himpfen H, Ginster T, Tenhagen I, Doeppner TR, Jockwitz C, Miller T, Lehmann N, Moebus S, Jöckel KH, Erbel R, Caspers S, Hermann DM; Heinz Nixdorf Recall Study Investigative Group. (2023) „Association of regional white matter hyperintensities with hypertension and cognition in the population-based 1000BRAINS study.“ Eur J Neurol. :1174-1190. PMID: 36702775.
- Jabbarli R, Darkwah Oppong M, Chihi M, Dinger TF, Said M, Rodemerk J, Dammann P, Schmidt B, Deuschl C, Guberina N, Wrede KH, Sure U. (2023) „Regular medication as a risk factor for intracranial aneurysms: A comparative case-control study.“ Eur Stroke J. :251-258. PMID: 37021158; PMCID: PMC10069188.
- Girschik C, Muchalla P, Kowall B, Zwanziger D, Erbel R, Ittermann T, Meisinger C, Stang A, Jöckel KH, Führer D. (2023) „Regionale Unterschiede von Schilddrüsenfunktionsparametern: ein Vergleich europäischer Kohortenstudien [Regional Differences in Thyroid Function Parameters: A Comparison of European Cohort Studies].“ Gesundheitswesen.:175-180. German. PMID: 36195110.
- Drogge SC, Frank M, Girschik C, Jöckel KH, Führer-Sakel D, Schmidt B. (2023) „Modification of TSH-related genetic effects by indicators of socioeconomic position.“ Endocr Connect.:e220127. PMID: 36547002.
- Erbel R, Lehmann N, Schramm S, Schmidt B, Hüsing A, Kowall B, Hermann DM, Gronewold J, Schmermund A, Möhlenkamp S, Moebus S, Grönemeyer D, Seibel R, Stang A, Jöckel KH. (2023) „Diagnostic Cardiac CT for the Improvement of Cardiovascular Event Prediction.“ Dtsch Arztebl Int. 20;120(3):25-32. PMID: 36518091.
- Krämer C, Stumme J, da Costa Campos L, Rubbert C, Caspers J, Caspers S, Jockwitz C. (2023) „Classification and prediction of cognitive performance differences in older age based on brain network patterns using a machine learning approach.“ Netw Neurosci. 1;7(1):122-147. PMID: 37339286.
- S. Stolpe, B. Kowall, D. Zwanziger, M. Frank, K. H. Jöckel, R. Erbel, et al. (2022). „External validation of six clinical models for prediction of chronic kidney disease in a German population.“ BMC Nephrol 23(1): 272. PMID: 35915408
- M. Specka, C. Weimar, A. Stang, K. H. Jöckel, N. Scherbaum, S. S. Hoffmann, et al. (2022). „Trail Making Test Normative Data for the German Older Population.“ Arch Clin Neuropsychol 37(1): 186-198.
- E. Matusch, M. Frank, K. Kara, A. A. Mahabadi, N. Dragano, R. Erbel, et al.(2022). „Impact of socioeconomic and cardiovascular risk factors on the effect of genetic variants associated with NT-proBNP.“ Sci Rep 12(1): 15560. PMID: 36114409
- S. Lucht, L. Glaubitz, S. Moebus, S. Schramm, C. Jockwitz, S. Caspers, et al. (2022). „Long-term air pollution, noise, and structural measures of the Default Mode Network in the brain: Results from the 1000BRAINS cohort.“ Int J Hyg Environ Health 239: 113867. PMID: 34717183
- M. Jokisch, S. Schramm, C. Weimar, S. Moebus, J. Gronewold, N. Dragano, et al (2022). „Fluctuation of depressive symptoms in cognitively unimpaired participants and the risk of mild cognitive impairment 5 years later: Results of the Heinz Nixdorf Recall study.“ Frontiers in Behavioral Neuroscience 16.
- J. Hovanec, T. Weiss, H. M. Koch, B. Pesch, T. Behrens, B. Kendzia, et al. (2022). „Smoking intensity and urinary nicotine metabolites by socioeconomic status in the Heinz Nixdorf Recall study.“ BMC Public Health 22(1): 10. PMID: 35164711
- J. Gronewold, M. Jokisch, S. Schramm, H. Himpfen, T. Ginster, I. Tenhagen, et al. (2022). „Periventricular rather than deep white matter hyperintensities mediate effects of hypertension on cognitive performance in the population-based 1000BRAINS study.“ Journal of Hypertension. PMID: 35983864
- J. Gronewold, E. E. Duman, M. Engel, M. Engels, J. Siegrist, R. Erbel, et al. (2022). „Association between life events and later depression in the population-based Heinz Nixdorf Recall study-The role of sex and optimism.“ PLoS One 17(7): 15. PMID: 35857802
- C. Girschik, P. Muchalla, B. Kowall, D. Zwanziger, R. Erbel, T. Ittermann, et al. (2022). „[Regional Differences in Thyroid Function Parameters: A Comparison of European Cohort Studies].“ Gesundheitswesen. PMID: 36195110
- M. Cainzos-Achirica, R. Quispe, R. Mszar, R. Dudum, M. Al Rifai, R. Erbel, et al. (2022). „Coronary Artery Calcium Score to Refine the Use of PCSK9i in Asymptomatic Individuals: A Multicohort Study.“ J Am Heart Assoc 11(16): e025737. PMID: 35943062
- M. Cainzos-Achirica, R. Quispe, R. Dudum, P. Greenland, D. Lloyd-Jones, J. S. Rana, et al. (2022). „CAC for Risk Stratification Among Individuals With Hypertriglyceridemia Free of Clinical Atherosclerotic Cardiovascular Disease.“ JACC Cardiovasc Imaging 15(4): 641-651. PMID: 34922873
- N. Bittner, H. W. Korf, J. Stumme, C. Jockwitz, S. Moebus, B. Schmidt, et al. (2022). „Multimodal investigation of the association between shift work and the brain in a population-based sample of older adults.“ Sci Rep 12(1): 2969. PMID: 35194054
- Alkhalawi E, Orban E, Schramm S, Katsarava Z, Hoffmann B, Moebus S (2021) Residential traffic noise exposure and headaches: Results from the population-based heinz nixdorf recall study. Noise & Health 23, 1-10. DOI: 10.4103/nah.NAH_1_20.
- Cainzos-Achirica M, Quispe R, Dudum R, Greenland P, Lloyd-Jones D, Rana JS, Lima JAC, Doria de Vasconcellos H, Joshi PH, Khera A, Ayers C, Erbel R, Stang A, Jöckel KH, Lehmann N, Schramm S, Schmidt B, Toth PP, Patel KV, Blaha MJ, Bittencourt M, Nasir K (2021). CAC for Risk Stratification Among Individuals With Hypertriglyceridemia Free of Clinical Atherosclerotic Cardiovascular Disease. JACC Cardiovasc Imaging. 2021 Dec 8:S1936-878X(21)00835-4. doi: 10.1016/j.jcmg.2021.10.017.
- Chen J, Rodopoulou S, de Hoogh K, Strak M, Andersen ZJ, Atkinson R, Bauwelinck M, Bellander T, Brandt J, Cesaroni G, Concin H, Fecht D, Forastiere F, Gulliver J, Hertel O, Hoffmann B, Hvidtfeldt UA, Janssen NAH, Jockel KH, Jorgensen J, Katsouyanni K, Ketzel M, Klompmaker JO, Lager A, Leander K, Liu S, Ljungman P, MacDonald CJ, Magnusson PKE, Mehta A, Nagel G, Oftedal B, Pershagen G, Peters A, Raaschou-Nielsen O, Renzi M, Rizzuto D, Samoli E, van der Schouw YT, Schramm S, Schwarze P, Sigsgaard T, Sorensen M, Stafoggia M, Tjonneland A, Vienneau D, Weinmayr G, Wolf K, Brunekreef B, Hoek G (2021) Long-Term Exposure to Fine Particle Elemental Components and Natural and Cause-Specific Mortality-a Pooled Analysis of Eight European Cohorts within the ELAPSE Project. Environ Health Perspect 129, 47009. https://doi.org/10.1289/EHP8368.
- Collaboration NCDRF. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet (London, England). 2021;398(10304):957-80. https://doi.org/10.1016/S0140-6736(21)01330-1.
- Collaboration NCDRF. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. Elife. 2021;10. https://doi.org/10.7554/eLife.60060.
- Demirer I, Schmidt B, Schramm S, Erbel R, Jöckel KH, Pförtner TK (2021): Does allostatic load predict incidental coronary events differently among sexes? Comprehensive Psychoneuroendocrinology Volume 8, November 2021, https://doi.org/10.1016/j.cpnec.2021.100089.
- Emmel C, Frank M, Nico Dragano, Nöthen MM, Erbel R, Jöckel KH, Schmidt B (2021). A genetic sum score of effect alleles associated with serum lipid concentrations interacts with educational attainment. Scientific Reports 2021 11:16541. https://doi.org/10.1038/s41598-021-95970-z
- Frank M, Hensel J, Baak L, Schramm S, Dragano N, Weimar C, et al. Interaction of Alzheimer’s Disease-Associated Genetic Risk with Indicators of Socioeconomic Position on Mild Cognitive Impairment in the Heinz Nixdorf Recall Study. J Alzheimers Dis. 2021;82(4):1715-25. PMID: 34219719.
- Gronewold J, Kropp R, Lehmann N, Stang A, Mahabadi AA, Weimar C, et al. Population impact of different hypertension management guidelines based on the prospective population-based Heinz Nixdorf Recall study. BMJ Open. 2021;11(2):e039597. PMID: 33597131.
- Hornung N, Frank M, Dragano N, Dürig J, Dührsen U, Moebus S, Erbel R, Stang A, Jöckel KH, Schmidt B (2021). Monoclonal gammopathy of undetermined significance is associated with prostate cancer in a population‑based cohort study. Scientific Reports 2021 11:19266. https://doi.org/10.1038/s41598-021-98803-1
- Icks A, Wittgens C, Haastert B, Jockel KH, Engel M, Erbel R, et al. High Depressive Symptoms in Previously Undetected Diabetes – 10-Year Follow-Up Results of the Heinz Nixdorf Recall Study. Clin Epidemiol. 2021;13:429-38. PMID: 34140811.
- Kowall B, Lehnich AT, Schramm S, Schmidt B, Erbel R, Jockel KH, et al. Family aggregation of sleep characteristics: Results of the Heinz Nixdorf Recall and the Multi-Generation Study. PLoS One. 2021;16(6):e0252828. PMID: 34086822.
- Kowall B, Rathmann W, Kuss O, Herder C, Roden M, Stang A, et al. Associations between haemoglobin A1c and mortality rate in the KORA S4 and the Heinz Nixdorf Recall population-based cohort studies. Diabetes Metab Res Rev. 2021;37(2):e3369. PMID: 32558166.
- Lucht S, Glaubitz L, Moebus S, Schramm S, Jockwitz C, Caspers S, Hoffmann B (2021) Long-term air pollution, noise, and structural measures of the Default Mode Network in the brain: Results from the 1000BRAINS cohort. Int J Hyg Environ Health 239, 113867. DOI: 10.1016/j.ijheh.2021.113867.
- Ohlwein S, Hennig F, Lucht S, Schmidt B, Eisele L, Arendt M, et al. Air Pollution and Polyclonal Elevation of Serum Free Light Chains: An Assessment of Adaptive Immune Responses in the Prospective Heinz Nixdorf Recall Study. Environ Health Perspect. 2021;129(2):27004. PMID: 33596105.
- Pechlivanis S, Jung D, Moebus S, Lehmann N, Mahabadi AA, Hoffmann P, et al. Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors -results of the Heinz Nixdorf Recall Study. Naunyn Schmiedebergs Arch Pharmacol. 2021;394(8):1713-25. PMID: 34021798.
- Rudman M, Frank M, Emmel C, Matusch E, Kara K, Mahabadi AA, et al. Socioeconomic position is associated with N-terminal pro-brain natriuretic peptide (NT-proBNP)-Results of the population-based Heinz Nixdorf Recall study. PLoS One. 2021;16(8):e0255786. PMID: 34415953.
- Schramm S, Jokisch M, Jockel KH, Herring A, Keyvani K. Is kallikrein-8 a blood biomarker for detecting amnestic mild cognitive impairment? Results of the population-based Heinz Nixdorf Recall study. Alzheimers Res Ther. 2021;13(1):202. PMID: 34930454.
- Schramm S, Schliephake L, Himpfen H, Caspers S, Erbel R, Jockel KH, et al. Vitamin D and white matter hyperintensities: results of the population-based Heinz Nixdorf Recall Study and 1000BRAINS. Eur J Neurol. 2021;28(6):1849-58. PMID: 33686727.
- Schramm S, Tenhagen I, Schmidt B, Holle-Lee D, Naegel S, Katsarava Z, et al. Prevalence and risk factors of migraine and non-migraine headache in older people – results of the Heinz Nixdorf Recall study. Cephalalgia. 2021;41(6):649-64. PMID: 33269953.
- Schulz CA, Mavarani L, Reinsch N, Albayrak-Rena S, Potthoff A, Brockmeyer N, Hower M, Erbel R, Jöckel KH, Schmidt B, Esser S; HIV HEART Aging Study Group and Heinz Nixdorf Recall Investigative Group (2021). Prediction of future cardiovascular events by Framingham, SCORE and asCVD risk scores is less accurate in HIV-positive individuals from the HIV-HEART Study compared with the general population. HIV Med. 2021 Sep;22(8):732-741. doi: 10.1111/hiv.13124. Epub 2021 May 24.
- Stolpe S, Kowall B; Zwanziger D, Frank M, Jöckel KH, Erbel R, Stang A (2021). External validation of six clinical models for prediction of unknown chronic kidney disease in a German population. doi: https://doi.org/10.1101/2021.12.23.21268085
- Strak M, Weinmayr G, Rodopoulou S, Chen J, de Hoogh K, Andersen ZJ, Atkinson R, Bauwelinck M, Bekkevold T, Bellander T, Boutron-Ruault MC, Brandt J, Cesaroni G, Concin H, Fecht D, Forastiere F, Gulliver J, Hertel O, Hoffmann B, Hvidtfeldt UA, Janssen NAH, Jockel KH, Jorgensen JT, Ketzel M, Klompmaker JO, Lager A, Leander K, Liu S, Ljungman P, Magnusson PKE, Mehta AJ, Nagel G, Oftedal B, Pershagen G, Peters A, Raaschou-Nielsen O, Renzi M, Rizzuto D, van der Schouw YT, Schramm S, Severi G, Sigsgaard T, Sorensen M, Stafoggia M, Tjonneland A, Verschuren WMM, Vienneau D, Wolf K, Katsouyanni K, Brunekreef B, Hoek G, Samoli E (2021) Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis. BMJ 374, n1904. doi: https://doi.org/10.1136/bmj.n1904.
- Wolf K, Hoffmann B, Andersen ZJ, Atkinson RW, Bauwelinck M, Bellander T, Brandt J, Brunekreef B, Cesaroni G, Chen J, de Faire U, de Hoogh K, Fecht D, Forastiere F, Gulliver J, Hertel O, Hvidtfeldt UA, Janssen NAH, Jorgensen JT, Katsouyanni K, Ketzel M, Klompmaker JO, Lager A, Liu S, MacDonald CJ, Magnusson PKE, Mehta AJ, Nagel G, Oftedal B, Pedersen NL, Pershagen G, Raaschou-Nielsen O, Renzi M, Rizzuto D, Rodopoulou S, Samoli E, van der Schouw YT, Schramm S, Schwarze P, Sigsgaard T, Sorensen M, Stafoggia M, Strak M, Tjonneland A, Verschuren WMM, Vienneau D, Weinmayr G, Hoek G, Peters A, Ljungman PLS (2021) Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts within the ELAPSE project. Lancet Planet Health 5, e620-e632. https://doi.org/10.1016/S2542-5196(21)00195-9.
- Zamrik T, Frank M, Emmel C, Rump LC, Erbel R, Jockel KH, et al. Association between socioeconomic position and cystatin C in the Heinz Nixdorf Recall Study. Sci Rep. 2021;11(1):19387. PMID: 34588554.
- K. Wichert, S. Rabstein, A. Stang, R. Erbel, L. Eisele, M. Arendt, et al. (2020). „Associations between shift work and risk of colorectal cancer in two German cohort studies.“ Chronobiol Int 37(8): 1235-1243. PMID: 32654542
- T. Weber, S. Wassertheurer, B. Hametner, C. C. Mayer, S. Moebus, S. Schramm, et al. (2020). „Additive prognostic value of vascular aging and coronary artery calcium for all-cause mortality in the Heinz Nixdorf Recall Study.“ European Heart Journal 41: 2824-2824.
- L. Tzivian, V. Soppa, A. Winkler, F. Hennig, C. Weimar, S. Moebus, et al. (2020). „The role of depressive symptoms within the association of long-term exposure to indoor and outdoor traffic noise and cognitive function – Results from the Heinz Nixdorf Recall study.“ Int J Hyg Environ Health 230: 113570. PMID: 32823068
- W. Sondermann, D. A. Djeudeu Deudjui, A. Korber, U. Slomiany, T. J. Brinker, R. Erbel, et al. (2020). „Psoriasis, cardiovascular risk factors and metabolic disorders: sex-specific findings of a population-based study.“ J Eur Acad Dermatol Venereol 34(4): 779-786. PMID: 31797464
- V. Rodins, S. Lucht, S. Ohlwein, F. Hennig, V. Soppa, R. Erbel, et al. (2020). „Long-term exposure to ambient source-specific particulate matter and its components and incidence of cardiovascular events – The Heinz Nixdorf Recall study.“ Environ Int 142: 14. PMID: 32590280
- O. Pelka, C. M. Friedrich, F. Nensa, C. Monninghoff, L. Bloch, K. H. Jöckel, et al. (2020). „Sociodemographic data and APOE-epsilon4 augmentation for MRI-based detection of amnestic mild cognitive impairment using deep learning systems.“ PLoS One 15(9): e0236868. PMID: 32976486
- S. Pechlivanis, S. Moebus, N. Lehmann, R. Erbel, A. A. Mahabadi, P. Hoffmann, et al. (2020). „Genetic risk scores for coronary artery disease and its traditional risk factors: Their role in the progression of coronary artery calcification-Results of the Heinz Nixdorf Recall study.“ PLoS One 15(5): e0232735. PMID: 32379805
- S. Pechlivanis, A. A. Mahabadi, P. Hoffmann, M. M. Nothen, M. Broecker-Preuss, R. Erbel, et al. (2020). „Association between lipoprotein(a) (Lp(a)) levels and Lp(a) genetic variants with coronary artery calcification.“ BMC Med Genet 21(1): 10. PMID: 32220223
- S. Pechlivanis, N. Lehmann, P. Hoffmann, M. M. Nothen, K. H. Jöckel, R. Erbel, et al.. (2020). „Risk prediction for coronary heart disease by a genetic risk score – results from the Heinz Nixdorf Recall study.“ BMC Med Genet 21(1): 178. PMID: 32912153
- R. Nussbaum, S. Lucht, C. Jockwitz, S. Moebus, M. Engel, K. H. Jöckel, et al. (2020). „Associations of Air Pollution and Noise with Local Brain Structure in a Cohort of Older Adults.“ Environ Health Perspect 128(6): 67012. PMID: 32539589
- S. Lucht, F. Hennig, S. Moebus, S. Ohlwein, C. Herder, B. Kowall, et al (2020). „All-source and source-specific air pollution and 10-year diabetes Incidence: Total effect and mediation analyses in the Heinz Nixdorf recall study.“ Environ Int 136: 105493. PMID: 31991234
- C. Li, J. Schreiber, N. Bittner, S. Li, R. Huang, S. Moebus, et al. (2020). „White Matter Microstructure Underlies the Effects of Sleep Quality and Life Stress on Depression Symptomatology in Older Adults.“ Front Aging Neurosci 12: 578037. PMID: 33281597
- B. Kowall, A. Stang, R. Erbel, S. Moebus, A. Petersmann, A. Steveling, et al. (2020). „Is the Obesity Paradox in Type 2 Diabetes Due to Artefacts of Biases? An Analysis of Pooled Cohort Data from the Heinz Nixdorf Recall Study and the Study of Health in Pomerania.“ Diabetes Metabolic Syndrome and Obesity-Targets and Therapy 13: 1989-2000. PMID: 32606858
- S. Klenke, N. Lehmann, R. Erbel, K. H. Jöckel, W. Siffert, U. H. Frey, et al. (2020). „Genetic variations in G-protein signal pathways influence progression of coronary artery calcification: Results from the Heinz Nixdorf Recall study.“ Atherosclerosis 310: 102-108. PMID: 32680596
- N. E. M. Jaspers, M. J. Blaha, K. Matsushita, Y. T. van der Schouw, N. J. Wareham, K. T. Khaw, et al. (2020). „Prediction of individualized lifetime benefit from cholesterol lowering, blood pressure lowering, antithrombotic therapy, and smoking cessation in apparently healthy people.“ Eur Heart J 41(11): 1190-1199. PMID: 31102402
- F. Hennig, M. H. Geisel, H. Kälsch, S. Lucht, A. A. Mahabadi, S. Moebus, et al. (2020). „Air Pollution and Progression of Atherosclerosis in Different Vessel Beds-Results from a Prospective Cohort Study in the Ruhr Area, Germany.“ Environ Health Perspect 128(10): 9. PMID: 33017176
- J. Gronewold, R. Kropp, N. Lehmann, B. Schmidt, S. Weyers, J. Siegrist, et al. (2020). „Association of social relationships with incident cardiovascular events and all-cause mortality.“ Heart 106(17): 1317-1323. PMID: 32165451
- M. Engel, K. H. Jöckel, N. Dragano, M. Engels and S. Moebus. (2020). „Subgroups with typical courses of depressive symptoms in an elderly population during 13 years of observation: Results from the Heinz Nixdorf Recall Study.“ Int J Soc Psychiatry 66(8): 799-809. PMID: 32583736
- D. Djeudeu, M. Engel, K. H. Jöckel, S. Moebus and K. Ickstadt (2020). „Spatio-temporal analysis of the risk of depression at district-level and association with greenness based on the Heinz Nixdorf Recall Study.“ Spat Spatiotemporal Epidemiol 33: 100340. PMID: 32370935
- I. Brandt, M. T. Puth, C. Kersting, S. Moebus, R. Erbel, K. H. Jöckel, et al. (2020). „No difference in medication regimes and dosing in study participants with and without blood pressure control: longitudinal data of the population-based Heinz Nixdorf Recall Study.“ Journal of Hypertension 38(3): 504-510. PMID: 31764588
- C. Brachem, A. Winkler, S. Tebrugge, C. Weimar, R. Erbel, K. H. Jöckel, et al. (2020). „Associations between self-reported sleep characteristics and incident mild cognitive impairment: The Heinz Nixdorf Recall Cohort Study.“ Sci Rep 10(1): 12. PMID: 32300149
- T. Weber, S. Wassertheurer, B. Hametner, S. Moebus, N. Pundt, A. A. Mahabadi, et al. (2019). „Cross-sectional analysis of pulsatile hemodynamics across the adult life span: reference values, healthy and early vascular aging: the Heinz Nixdorf Recall and the MultiGeneration Study.“ Journal of Hypertension 37(12): 2404-2413. PMID: 31246896
- J. Gronewold, R. Kropp, N. Lehmann, A. Stang, A. A. Mahabadi, H. Kälsch, et al. (2019). „Cardiovascular Risk and Atherosclerosis Progression in Hypertensive Persons Treated to Blood Pressure Targets.“ Hypertension 74(6): 1436-1447. PMID: 31679426
- R. A. Abbott, C. Skirrow, M. Jokisch, M. Timmers, J. Streffer, L. van Nueten, et al. (2019). „Normative data from linear and nonlinear quantile regression in CANTAB: Cognition in mid-to-late life in an epidemiological sample.“ Alzheimers Dement (Amst) 11(1): 36-44. PMID: 30623017 dec
- M. Engels, S. Weyers, S. Moebus, K. H. Jöckel, R. Erbel, B. Pesch, et al. (2019). „Gendered work-family trajectories and depression at older age.“ Aging Ment Health 23(11): 1478-1486. PMID: 30621439
- B. Schmidt, E. Debold, M. Frank, M. Arendt, N. Dragano, J. Dürig, et al. (2019). „Socioeconomic Position is Positively Associated with Monoclonal Gammopathy of Undetermined Significance in a Population-based Cohort Study.“ Ann Hematol 98(12): 2761-2767.
- S. Pechlivanis, S. Heilmann-Heimbach, R. Erbel, A. A. Mahabadi, L. M. Hochfeld, K. H. Jöckel, et al. (2019). „Male-pattern baldness and incident coronary heart disease and risk factors in the Heinz Nixdorf Recall Study.“ PLoS One 14(11): e0225521. PMID: 31743359
- S. Ohlwein, F. Hennig, S. Lucht, C. Matthiessen, N. Pundt, S. Moebus, et al.. (2019). „Indoor and outdoor road traffic noise and incident diabetes mellitus: Results from a longitudinal German cohort study.“ Environ Epidemiol 3(1): e037. PMID: 33778334
- M. Frank, N. Dragano, M. Arendt, A. J. Forstner, M. M. Nothen, S. Moebus, et al. (2019). „A genetic sum score of risk alleles associated with body mass index interacts with socioeconomic position in the Heinz Nixdorf Recall Study.“ PLoS One 14(8): 14. PMID: 31442235
- Hovanec, J., J. Hovanec, T. Weiss, H. Koch, B. Pesch, T. Behrens, B. Kendzia, et al. (2019). „Smoking and urinary cotinine by socioeconomic status in the Heinz Nixdorf Recall Study.“ J Epidemiol Community Health 73(6): 489-495. PMID: 30804047
- B. Kowall, R. Erbel, S. Moebus, N. Lehmann, K. Kröger and A. Stang (2019). „Decline in ankle-brachial index is stronger in poorly than in well controlled diabetes: Results from the Heinz Nixdorf Recall cohort study.“ Atherosclerosis 284: 37-43. PMID: 30870706
- M. Wahrendorf, A. Marr, M. Antoni, B. Pesch, K. H. Jöckel, T. Lunau, et al.. (2019). „Agreement of Self-Reported and Administrative Data on Employment Histories in a German Cohort Study: A Sequence Analysis.“ Eur J Popul 35(2): 329-346. PMID: 31105502
- D. Müller-Gerards, C. Weimar, J. Abramowski, S. Tebrugge, M. Jokisch, N. Dragano, et al. (2019). „Subjective cognitive decline, APOE epsilon4, and incident mild cognitive impairment in men and women.“ Alzheimers Dement (Amst) 11(1): 221-230. PMID: 30891488
- M. Caputo, J. Horn, A. Karch, M. K. Akmatov, H. Becher, B. Braun, et al.. (2019). „Herpes zoster incidence in Germany – an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort.“ BMC Infect Dis 19(1):
- N. Bittner, C. Jockwitz, T. W. Muhleisen, F. Hoffstaedter, S. B. Eickhoff, S. Moebus, et al. (2019). „Combining lifestyle risks to disentangle brain structure and functional connectivity differences in older adults.“ Nature Communications 10: 13.
- S. Lucht, F. Hennig, S. Moebus, D. Fuhrer-Sakel, C. Herder, K. H. Jockel, et al.
- (2019). „Air pollution and diabetes-related biomarkers in non-diabetic adults: A pathway to impaired glucose metabolism?“ Environment International 124: 370-392.
- B. Kowall, N. Lehmann, A. A. Mahabadi, S. Moebus, R. Erbel, K. H. Jöckel and A. Stang (2019). „Associations of metabolically healthy obesity with prevalence and progression of coronary artery calcification: Results from the Heinz Nixdorf Recall Cohort Study.“ Nutr Metab Cardiovasc Dis 29(3): 228-235. PMID: 30648599
- H. Kälsch, A. A. Mahabadi, S. Moebus, N. Reinsch, T. Budde, B. Hoffmann, et al. (2019). „Association of progressive thoracic aortic calcification with future cardiovascular events and all-cause mortality: ability to improve risk prediction? Results of the Heinz Nixdorf Recall (HNR) study.“ Eur Heart J Cardiovasc Imaging 20(6): 709-717.