The PhD program „Epidemiology and Clinical Research“ is a three-year, structured and internationally oriented doctoral program. Within the University Alliance Ruhr, the Institute of Medical Informatics, Biometry and Epidemiology (IMIBE) of the University Medicine Essen, the Department of Mathematical Statistics and Biometric Applications of the Technical University Dortmund, the Department of Medical Informatics, Biometry and Epidemiology and the Institute of Prevention and Occupational Medicine of the German Social Accident Insurance of the Ruhr-University Bochum are involved in the PhD program.
The program is designed to enable doctoral candidates to independently plan, conduct, analyze and publish studies on epidemiological and clinical issues (early detection, diagnosis, therapy and prognosis), taking into account Good Epidemiological Practice (GEP) and Good Clinical Practice (GCP). With the dissertation, the doctoral candidates prove that they achieve results through independent scientific work that serve the further development of the epidemiological field and clinical medicine.
The three-year doctoral program includes the integration into an own research project and an accompanying program designed for two years, which comprises a total of at least 300 teaching units (LE) of 45 minutes each. 263 units are compulsory and selectable modules. 37 LE can be freely chosen and are used to form focus competencies in epidemiology. The courses are offered as block courses in module form as 3-day or weekly courses. This means that the different knowledge, skills and abilities enabling the dissertation are acquired in complementary courses that build on each other. In 2 weeks per semester in each of the 1st and 2nd years of study, courses are held at the IMIBE/University Hospital in Essen. During the doctoral studies, presence at the IMIBE/University Hospital in Essen is only required for the courses and the 3-day RUHR School.
Among others, the following mandatory modules are part of the PhD program:
- Statistics program with SAS
- Medicine for non-physicians
At the Ruhr School, guest lecturers offer interesting topics in the fields of epidemiology and clinical research.
During the PhD program, the PhD students will be accompanied by two supervisors.
The third year of the PhD program is used to finalize the dissertation. Upon successful completion of the PhD program, the Medical Faculty of the University of Duisburg-Essen awards the academic degree „Doctor of Philosophy (PhD)“.
The teaching language is English.
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Nader Hirmas, jordanischer Nationalität, hat einen Bachelor of Science in Biologie sowie einen Doktortitel in Medizin (M.D.) von der Amerikanischen Universität Beirut (2008–2015). Nach seinem Abschluss arbeitete er im Bereich der Krebsforschung, insbesondere in der pädiatrischen Onkologie und der Nuklearmedizin. 2018 erhielt er ein Stipendium des Deutschen Akademischen Austauschdienstes (DAAD) für seine Promotion in Medizinwissenschaften (Dr. rer. Medic.) in der Abteilung für Nuklearmedizin des Universitätsklinikums Essen mit dem Schwerpunkt Diagnose und Staging von Leber- und Prostatatumoren mittels molekularer Bildgebung (PSMA PET). Ziel seines Epidemiologie-PhD-Projektes ist es, die diagnostische Genauigkeit der molekularen Bildgebung mit dem neuartigen FAPI-46-PET-Tracer und seine Auswirkungen auf das Staging und das klinische Management von Patienten mit verschiedenen Krebsentitäten zu bewerten.
Robin Denz ist wissenschaftlicher Mitarbeiter an der Ruhr-Universität Bochum in der Abteilung für Medizinische Informatik, Biometrie und Epidemiologie. Zwischen 2014 und 2020 absolvierte er ein Studium der Soziologie (Bachelor of Arts) und der Survey Methodology (Master of Arts) an der Universität Duisburg-Essen. In seiner Position als Wissenschaftler an der Ruhr-Universität Bochum beschäftigt er sich mit der Planung und statistischen Analyse verschiedener medizinischer Studien. Eines seiner Forschungsinteressen ist die Weiterentwicklung von Datenanalysemethoden in der medizinischen Statistik. Sein Promotionsprojekt beschäftigt sich mit dem Vergleich verschiedener Methoden zur Berechnung von Confounder-adjustierten Überlebenskurven und kumulativen Inzidenzfunktionen.
Dr. Katharina Marie Steiner
Katharina Marie Steiner works as a physician in the department of psychiatry at LVR Klinikum Essen, Essen University. She studied medicine at Essen University Hospital and finished her doctoral thesis (MD) on Reelin signaling pathway and Alzheimer’s pathology in 2013 at the institute of neuropathology, Essen University Hospital. KMS started her clinical career in the department of neurology, Essen University Hospital in 2014 and completed her specialized training before she moved over to the psychiatric department. In October 2020 she received the UMEA clinician scientist grant (Universitätsmedizin Essen Clinician Scientist Academy), that will finance her release from clinical work in the half of the time during three years. Her research focus is on the overlap of both neurological and psychiatric scientific issues: her previous research projects addressed associative learning and motor learning in the context of cerebellar functioning and disease using stimulation techniques as transcranial direct current stimulation and MRI techniques as voxel based morphometry and lesion symptom mapping. In her PhD project she is going to analyze the effects of treatment expectation towards transcranial magnetic stimulation in patients with major depressive disorder. Research will be carried out in particular to investigate the neuronal networks underlying both depression and expectation and a possible cerebellar involvement in these networks.
Anne Lotz studied statistics at the TU Dortmund with a focus on Biometrics. Since 2005, she works in the competence center of epidemiology at the Institute of Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), which is an Institute of the Ruhr University Bochum (https://ipa-dguv.de). Anne Lotz analyzed the association between workplace exposures and health effects in a variety of epidemiologic studies (ORCID https://orcid.org/0000-0002-8715-0743). Her recent research focuses on the analysis of left censored variables. Censored variables occur for example when measurement methods are not sensitive enough to quantify low-exposures correctly and one or more measurements can only be characterized as being less than a limit of detection. As exposure limits decrease and methods for exposure reduction improve these kinds of datasets might occur more frequently. In her first project in context of her PhD thesis Anne Lotz will look at possibilities to extend the method of Bland-Altman to censored variables.
Dr. Kristina Boss
Kristina Boss is a physician at the University Hospital Essen. She studied medicine at the University Duisburg-Essen from 2012 to 2018 and received her doctorate degree (Dr. med.) in 2019. Since 2019, she is a resident physician at the Department of Nephrology. Her clinical and scientific interests are acute kidney injury and extracorporeal procedures. Her PhD project is focused on epidemiologic characteristics of the detection and graduation of kidney diseases.
Nicola Hornung hat in Essen Medizin studiert und absolviert derzeit ihre Facharztweiterbildung in der Abteilung für Anästhesiologie und Intensivmedizin der Universitätsklinik Düsseldorf. Während des Studiums hat sie das Krebs Follow Up der Heinz Nixdorf Recall Studie betreut und Studierendenkurse im Querschnittsbereich 1 „Medizinische Informatik, Biometrie und Epidemiologie“ unterrichtet. Im Rahmen ihrer ersten Dissertation befasste sie sich mit der Assoziation von Monoklonaler Gammopathie unklarer Signifikanz mit dem Auftreten von Prostatakarzinomen in der Heinz Nixdorf Recall Studie. In ihrem PhD-Projekt widmet sie sich mit einer Interaktionsanalyse der Frage, welche Rolle polygenetische Risikovarianten für den Zusammenhang zwischen Schlafstörungen und dem Auftreten von Koronarer Herzkrankheit spielen.
Dr. Julian Kleine-Borgmann
Julian Kleine-Borgmann is a clinician scientist and physician at the Department of Neurology at the University Medicine Essen. He completed his studies at the University Duisburg-Essen in 2015 and finalized his MD thesis in 2017, in which he investigated the impact of an experimental inflammatory response on central pain perception. Since 2020 he is supported by the UMEA Clinician Scientist Program. His research focusses on the interaction between cognition and pain processing and his PhD project will include meta-analytic approaches to investigate the effectiveness of placebo interventions in different conditions.
Benjamin Borchardt hat von 2006 bis 2013 Humanmedizin an der Medizinischen Universität Wien studiert. Er erlangte den Doktor der gesamten Heilkunde (Dr. med. univ.) durch eine Diplomarbeit in Kooperation mit der Tobacco Dependence Research an der Queen Mary University of London. Im selben Jahr beendete er ebenfalls sein Psychologiestudium an der Universität Wien, das er mit einem Bachlor of Science abschloss. In den letzten sechs Jahren war er in verschiedenen klinischen Fachbereichen tätig und befindet sich gegenwärtig im letzten Jahr seiner Facharztweiterbildung zum Allgemeinmediziner. Zurzeit ist er als Arzt in Weiterbildung am Institut für Allgemeinmedizin der Universität Duisburg-Essen tätig.
In seinem Ph.D.-Projekt beschäftigt er sich weiter mit dem Forschungsschwerpunkt Nikotinabhängigkeit. Sowohl Prädiktoren für den Rückfall zum Rauchen nach einer erfolgreichen Entwöhnungstherapie als auch Prädiktoren für Lungenkrebs sollen untersucht werden.
Alejandro Cabello López
Alejandro Cabello López ist ein mexikanischer Arzt, der seinen Bachelor in Medical Surgeon an der UNAM (2009-2015) erhielt. Nach seinem Abschluss arbeitete Alejandro anderthalb Jahre als wissenschaftlicher Mitarbeiter in der Arbeitsgesundheits-Forschungseinheit des mexikanischen Instituts für soziale Sicherheit. 2016 erhielt Alejandro das Karolinska Institutet Global Master’s Scholarship und schrieb sich für das Masterprogramm Public Health Epidemiology ein. Seine Masterarbeit bewertete die Auswirkungen der beruflichen Exposition gegenüber organischen Lösungsmitteln und des Lärms auf das Hören. Nach seinem Abschluss am Karolinska Institutet begann Alejandro als Forscher in der oben genannten Forschungseinheit in Mexiko zu arbeiten, wo sich sein aktuelles Forschungsinteresse – und PhD-Thema – auf die Bewertung von Biomarkern für das Pleuramesotheliom-Screening in Asbest-exponierten Populationen konzentriert, ein Projekt, das seit 2015 mit der IPA Bochum zusammenarbeitet.
Dr. Philipp Jansen
Dr. Philipp Jansen, arbeitet als Facharzt für Haut- und Geschlechtskrankheiten an der Klinik für Dermatologie, Universitätsmedizin Essen. Nach dem Medizinstudium in Bonn und München hat er seine Promotion im Jahr 2015 abgeschlossen. Im Rahmen der Dissertation hat Dr. Jansen den Einfluss des Typ-I Interferonsystems auf die Wachstumskinetik von Melanomen in einem Mausmodell untersucht. Seit Juli 2020 beschäftigt er sich im Rahmen des UMEA Clinician Scientist Programms mit der histologischen und genetischen Charakterisierung von kutanen Tumoren. Zuletzt konnte er einen Start-up Grant für die Etablierung eines Mustererkennungsalgorithmus zur histologischen Gewebeanalyse einwerben. Im Rahmen seines PhD Projekts wird er die Ergebnisse seiner Forschungsarbeiten mit den klinischen Patientenverlaufsdaten in einer Datenbank zusammentragen und ein Prognosemodell für das Metastasierungsverhalten von Melanomen entwickeln.
Marianne Tokic studied Biopsychology and cognitive Neuroscience at Maastricht University and the Ruhr-University Bochum. Since December 2019 she is working at the Department of Medical Informatics, Biometry and Epidemiology of the Ruhr-University Bochum. In her research she mainly focuses on the effects of the suspension of disease modifying therapies in the context of multiple sclerosis and pregnancy.
Nora Bruns studied Medicine at the University of Rostock and Charité Berlin until 2009 and began her clinical career in Pediatrics in the surroundings of Berlin. Since 2012, she is working in the Department of Pediatrics of the University Hospital Essen. In 2019 she became a specialist in Pediatrics. She is planning to subspecialize in Pediatric Intensive Care. In 2012, she finished her doctorate thesis about amplitude-integrated EEG in preterm infants. Since then, her main research interests have been neuromonitoring and neurocritical care in neonates and children. For her PhD Project she will focus on pediatric traumatic brain injury.
Dr. med. Maximilian Falk is a physician at University Hospital Essen. He studied medicine at the University of Bonn from 2010 to 2016. Since 2017 he is conducting his Residency for internal medicine at the University Hospital of Essen. In 2018 he finished his doctor thesis (Dr. med.) about the influence of endogenous ligands on myocardial contractility after aortocoronary bypass surgery in Bonn. His research topic for the PhD is the development of a method for improved digitalization in the emergency room to improve patient care and evaluation of clinical datasets.
Ulrich Gehrmann graduated in Informatics at the University of Applied Sciences in Munich and worked as a software developer in the 1990s. Then he studied Statistics at the LMU Munich and received his diploma in 2003. From then on, he was employed as Biostatistician in the areas of pharmaceutical industry as well as health technology assessment. Since 2017 he works as a consultant in the Evidence Based Medicine department of the Medical Advisory Service of Social Health Insurance (MDS) in Essen. His tasks are biometrical advice in all assessments of new medical products as well as statistical programming, e.g. meta analyses. One of his research interests is the adequate assessment of treatment effects regardless of distribution presumptions (nonparametric statistics). In this regard, for the PhD he works on a generalization of the Number Needed to Treat (NNT) measurement to all kinds of scales and on an inclusion of the Minimal Important Difference (MID) within this generalized NNT.
Gerrit M. Große
Gerrit M. Große studied medicine at Hannover Medical School (MHH) and works in the Clinic of Neurology at MHH since January 2015. He obtained his Dr. med. degree in 2016 and is active in clinical research in the field of cerebrovascular diseases. The main focus of his work includes the improvement of etiological diagnostics and secondary prevention of ischemic stroke. Since 2019 he is supported by the Clinician Scientist Program PRACTIS, which is funded by the German Research Foundation. In accordance with his previous work his PhD project addresses issues concerning oral anticoagulation in patients who suffered stroke due to atrial fibrillation.
Mael Lever graduated in medicine from the Ruhr-University Bochum in 2014 and earned his doctor’s degree in 2018. After working as a resident in the Neurosurgery Department of the Klinikum Dortmund, he joined the Department of Ophthalmology of the University Hospital Essen in 2016. Mael’s clinical and scientific focus is on uveal melanoma and its immunological properties and also works on artificial intelligence-aided diagnostic methods in ophthalmology. His PhD project is centred around epidemiologic characteristics of uveal melanoma and the personal, molecular and therapeutic factors affecting the patient’s Outcome.
Uta Leyener is physiotherapist specialized in paediatrics. She finished her professional education in 2008 at the Alfried Krupp Krankenhaus in Essen. Directly afterwards she started her Bachelor´s Programme for physiotherapists at the University of Applied Sciences and Arts in Hildesheim. After the successful completion of the studies she worked as an employee in pediatric physiotherapy practices and started to teach at a professional school for physiotherapy. In 2014 she commenced her master studies in Adult Education at the Distance and Independent Studies Center (DISC) at Technische Universität Kaiserslautern and finished this programme in 2016. Since 2017 she has been working in the Sozialpädiatrisches Zentrum (SPZ) at the University Hospital Essen. Her responsibilities are therapeutic follow up diagnostics including standardized test procedures in infants, children and teenagers, medical aid consultation and physiotherapeutic function tests for clinical multicentre studies.
Her research focuses on motor development in preterm infants. A standardized assessment – the General Movements Assessment – enables to identify children at risk of neurological developmental disorder. An early and specific treatment involving parents is performed and its effect on motor development evaluated.
Julien Merta finished his studies with a master’s degree in public health at Bielefeld University in 2014. His master thesis focused on analysing evidence based public health and quality assurance strategies in health promotion and prevention projects. After working as a project manager in a healthcare consulting company Julien Merta joined the West German Proton Therapy Centre at the University Hospital Essen in 2016. Here he coordinates the reference radiotherapy and radiotherapy quality assurance programms in several pediatric oncology trials and registries as well as the Advisory Centre for Particle Therapy in Pediatric Oncology headed by Prof. Beate Timmermann. His research topics of interests are long-term follow-up care and patient reported outcomes in pediatric radiooncology. In his PhD project he analyses health related quality of life outcomes after proton beam therapy in patients with pediatric brain tumors.
Benjamin Kendzia finished his diploma in statistics at the TU Dortmund University in 2007. His major research interests are exposure assessment science and occupational epidemiology. He is scientist at the Institute for Prevention and Occupational Medicine of the German Social Accident Insurance – Institute of the Ruhr University Bochum (IPA) (https://ipa-dguv.de). The main focus of Benjamin’s research activities is the estimating of occupational exposure to a variety of known and suspected carcinogens for epidemiologic studies (ORCID https://orcid.org/0000-0002-8662-795X). His research project for the PhD program includes the measurement-based quantification of welding fume exposure and its effects on the health of employees.
Stephan Koslitz studied chemistry at university of applied sciences Gelsenkirchen (Germany) and Sion (Switzerland) until 2006. He is working since 2007 at the competence center toxicology, working group human biomonitoring, at the Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), which is an institute of the Ruhr University Bochum (Germany). As technical head of laboratory, his focus is on the development and establishment of analytical methods of toxicological concern. He is working on metabolites of polycyclic aromatic hydrocarbons (PAH), diisocyanates, solvents and volatile organic compounds additional on metals in blood and urine for exposure assessment at workplaces. In particular, for his PhD he assesses the internal body burden of workers, exposed to Benzo[a]pyrene, a carcinogenic PAH.
Norbert Nosal studied Medicine at the Ruhr-Universität Bochum until 2007 and began his clinical career in Gynecology and Obstetrics at the University Hospital Essen, where he also worked on various clinical studies. After further work at the Hospital Essen-Werden, he has been working at the academic teaching hospital Elisabeth Hospital Essen since 2010. Since 2012 he is a Specialist in Gynecology and Obstetrics and in 2014 he finished his doctoral thesis with Prof. Dr. med. Hahn at Ruhr University Bochum at Clinical Research Center (ZKF) in Department of Molecular GI Oncology (MGO). Since 2014 he is a Senior Physician and since 2019 Deputy Chief Physician. His clinical focus is on the treatment of female urinary incontinence and pelvic floor surgery, minimally invasive surgery, gynecological oncology and clinical obstetrics. Research focuses on female urinary incontinence therapies and the optimization of minimally invasive operations, in particular fertility-preserving and fertility-reconstructive therapies.
Christine Schmitz graduated in medicine from the University Hospital Hamburg-Eppendorf in 2011 and earned her doctor’s degree two years later. Since 2016 she is working in the Department of Hematology at the University Hospital of Essen. Here, she finished her training as specialist for internal medicine and hematology and oncology in 2018. In her research, she focuses on patient-reported outcomes after surviving hematological malignancies.
Rhim Shu (MD. MPH, Msc.), Cameroonian of nationality, successfully completed his medical degree as well as a specialization in Endocrinology at the Medical Institute of the Sumy State University in Ukraine (2006 – 2014). He later successfully obtained a Master Degree in Public Health at the University of Brussels, Belgium (2015 – 2016) focusing on retrospective cohort-analyses of associated pregnancy outcome risk factors of low birth weight and risky mode of delivery among Belgian women. Between 2016 – 2018, Dr. Rhim Shu obtained a Master Degree in Pharmaco- & Healtheconomics at the University of Applied Sciences – „Hochschule Fresenius“ in Idstein, Germany, wherein, predictive health state-transition cost-effectiveness modelling analyses of Type 2 Diabetes Mellitus management strategies were his main focus. Dr. Rhim Shu is currently a full-time scholarship awarded PhD researcher at the „Centre of Clinical Epidemiology – ZKE“ in affiliation to the „Institute of Medical Informatics, Biometrics and Epidemiology – IMIBE“ of the University of Duisburg-Essen (UDE), with research focussing on the influences of sex hormones on coronary and cardiovascular diseases, metabolic status and health outcomes of respondents of the Heinz Nixorf Recall (HNR) population based prospective cohort study in Germany, with Prof. Dr. rer. nat. K. H. Jöckel, PD Dr. med. S. Reger-Tan and Dr. rer. nat. Nils Lehmann as research Mentors.
Carolin Girschik studied Nutritional Sciences at the Justus-Liebig-University of Gießen and Martin-Luther-University of Halle (Saale). Within her master thesis she has been doing research in the field of dendritic cell vaccination to be used in tumor therapy at the Institute of Medical Immunology. In 2017, she also obtained a Master’s degree in Public Health from the University of Chemnitz. Her second master thesis was conducted at the ErasmusAGE group of the Erasmus Medical Center in Rotterdam while studying the association between macronutrient intake and coronary heart disease. During her studies she did various internships, e. g. at the German Nutrition Society (DGE) and the German National Cohort (GNC).
Her current research line at the Center of Clinical Epidemiology (CCE) in Essen focuses on the association between endocrinological and cardiovascular diseases among participants of the Heinz Nixdorf Recall Study cohort.
Janine Gronewold, born January 2nd 1987 in Ratingen, received her diploma in Psychology in 2010 at the University of Wuppertal. Her diploma thesis focused on psychophysiological responses to commercial products depending on advertisement and personality traits. In 2015 she earned her Dr. rer. nat. at the Faculty of Psychology of the Ruhr University Bochum under the mentorship of Prof. Hermann for her thesis „Prediction of incident stroke events in the population-based Heinz Nixdorf Recall study using subclinical atherosclerosis markers“. Since 2015 she works as post-doctoral scientist in the NeuroScienceLab at the Chair of Vascular Neurology, Dementia and Ageing Research, where she currently supervises a research group evaluating the role of vascular risk factors, medical treatment and subclinical atherosclerosis markers in stroke and cardiovascular disease development.
Sarah Knispel finished her university degree in medicine in 2012. Then, she started her clinical education and finished her dissertation during the first year of her residency. Supported by the supervising tutor, the dissertation resulted in a publication and was awarded with the Klaus-Dieter-Schulz-Versorgungspreis 2013. Since oncology has always been the focus of her interest, her research activities since finishing her dissertation are concentrated on melanoma. Currently, she is involved as a subinvestigator in several clinical phase I-III studies on patients with melanoma. In cooperation with consultant doctor Lisa Zimmer, she launched a retrospective multicenter analysis of patients with high LDH addressing the question of sequential therapy of immunotherapy and targeted therapy in patients with high LDH as these patients belong to a cohort with an especially high medical need.
Her research project for the PhD program is an explorative analysis addressing the questionable interactions between stress and depression and the immune system in melanoma patients. The activation of the immune system by PD-1 blockade is the most progressive therapeutical option in the field of dermatooncology and influence of stress on outcome parameters is insufficiently analyzed. The project is to be performed in collaboration with the department of medical psychology Essen (Prof. Schedlowski).
Susanne Stolpe finished her diploma in Bioscientific Documentation at the Fachhochschule Hannover in 1990. Until 2014 she was then an employee at the Department of Medical Informatics, Biometry and Epidemiology at the Ruhr-University Bochum. During this time she also completed her Master’s degree in Public Health at the Heinrich-Heine University Düsseldorf, where she continued to work as a research assistant until 2015. Since then she is part of the staff at the Center of Clinical Epidemiology at the University of Duisburg-Essen.
Marjan Amiri is a pharmacist by training. She finished her bachelor studies in Pharmaceutical Sciences in 2009 and her master studies in Pharmaceutical Medicine in 2015. She conducted an empirical project as her master thesis, in which she investigated the expectation and satisfaction of academic investigators from Western Europe, North America and Japan, when collaboration with pharmaceutical industries. She works since 2015 as a researcher and pharmacovigilance manager at the center of clinical studies at university hospital of Essen. Her research area is drug safety as well as analyzing the limitations, challenges and opportunities of non- interventional studies for the collection of real-life data and proposing methods which can be employed to increase their internal and external validity. She is currently involved in the statistical analysis of a number of non-interventional studies.
Katarzyna Wiktoria Burek is senior statistician at the Department of Epidemiology at the Institute for Prevention and Occupational Medicine (IPA) of the German Social Accident Insurance (DGUV), which is associated with the Ruhr University Bochum (Germany). She received her Diploma in Statistics from the TU Dortmund University (Germany) in 2010. Her research interests cover health related topics in occupational epidemiology including the application and development of statistical models. Much of her work is on the evaluation of disease biomarkers through data mining, advanced statistics, and performance evaluations. Her recent research focuses on the impact of shift work on circadian rhythms in humans. Specifically, for her PhD she assesses the influence of night work on the circadian profile of cortisol in female hospital staff.
Miriam Engel studied sociology at the University of Duisburg-Essen (Germany). As part of her master thesis in the Survey Methodology master’s programme, she conducted a meta-analysis of the willingness to participate in epidemiological and medical observational studies depending on the recruitment mechanism. Since 2015, Ms. Engel works at the Institute for Medical Informatics, Biometry and Epidemiology (IMIBE) at the University Hospital in Essen, where she initially developed a recruitment concept for the Heinz Nixdorf Recall MultiGenerationStudy and monitored the measures derived from it. Since 2016, she is the study coordinator of the 1000BRAINS Study. This Study investigates in cooperation with the Research Centre Jülich the process of normal brain aging in a group of 1000 participants of the Heinz Nixdorf Recall Study.
In her dissertation, Ms. Engel studies the longitudinal evaluation of depressive symptoms, also using data from the Heinz Nixdorf Recall Study.
Pietro Trocchi studied veterinary medicine in Bologna (Italy) and received his doctorate there. Since 2006 he has been working in Germany as a research associate and, in the context of this position, completed his supplementary studies in epidemiology at the BSPH of the Charité in Berlin with a Master of Science in Epidemiology (MSE) in 2009. His professional focus was the coordination and data analysis of very different projects, mainly in the field of cancer epidemiology. Since 2017 he has been working at the Institute for Medical Informatics, Biometry and Epidemiology (IMIBE) of the University Hospital Essen on a project within the funding program of the German Cancer Aid (Deutsche Krebshilfe) ‚Epidemiological Research with Cancer Registry Data‘. The title of the project is: „Breast cancer incidence and operation rates before, during and after implementation of the mammography screening program in Germany“. Furthermore, as part of the PhD program, he is conducting a study on the inpatient treatment of patients with ovarian cancer. In connection with the graduate program of the German Cancer Aid, he worked for three months as a guest researcher in the Cancer Registry of the German federal state of North Rhine-Westphalia with the aim of conducting a study on the incidence rates of ovarian cancer.
Katharina Wichert finished her Master’s degree in Statistics at the TU Dortmund University (Germany) in 2016. Her master thesis focused on the statistical analysis of the role of genes in melatonin biosynthesis and signaling in the development of breast cancer since melatonin can act on many different pathways on cellular level which also includes oncostatic actions. It was carried out at the Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), which is an institute of the Ruhr University Bochum (Germany). Since then, she works as a research assistant at the IPA and analyzes data from different epidemiological studies. In her projects regarding the PhD program, she analyzes health effects of shift work with regard to cancer development.
The application consists of a two-stage procedure.
For the first stage of the application, you will need the documents mentioned in points 1-8.
For the second stage, we will send you the required templates for items 9-12.
The following documents must be submitted for an application to the PhD program:
1. cover letter indicating aptitude, motivation, and areas of scientific interest, as well as ideas for further career development.
2. curriculum vitae
3. officially certified proof that the applicant meets the admission requirements of the PhD regulations of the Medical Faculty of the University of Duisburg-Essen according to § 5.
4. certified copy of the certificate entitling the holder to pursue undergraduate studies
5. proof of proficiency in the English language
6. signed statement on the preliminary topic of the intended dissertation by the supervisors
7. indication of the intended field of doctoral studies and outline of the doctoral plan
8. two letters of recommendation with reference to previous academic achievements and aptitude for scientific work
9. application for admission to the PhD program
10. statement indicating whether the applicant has already unsuccessfully attempted a doctoral degree
11. statement in which the applicant declares that participation in the PhD program will not be achieved through commercial mediation of the supervisory relationship or other paid and unpaid assistance by third parties that is inadmissible under examination law and scientifically unjustifiable
12. declaration by the intended supervisor that he/she is willing to supervise the dissertation and to continue to supervise it even if he/she leaves, unless there are important reasons for not doing so
Only complete applications will be considered.
Electronic applications must consist of a single PDF file.
Application deadline: February 15, 2023
Applicants from abroad must credibly explain in a short statement how participation in the PhD program will be achieved.
Applications are sent by mail to:
Institut für Medizinische Informatik, Biometrie und Epidemiologie (IMIBE)
z. Hd. Fabian Standl
D- 45147 Essen
or electronically to:
There are no scholarships available at this time.
Regulations for externally interested persons
Opening of the PHD program „Epidemiology Clinical Research“ in Essen for external participants.
Since the summer semester 2019, the modules of the PhD program „Epidemiology & Clinical Research“ are also open for externally interested participants.
Participation in the modules is subject to the following conditions:
|Non-University members||University members excluding members of the University of Duisburg-Essen||Students exclusive Ruhr Alliance students*|
|1 morning or afternoon||200 Euro||80 Euro||15 Euro|
The prices displayed are not binding. Please contact us by mail for binding information.
*Aimed at persons who are not in employment subject to social insurance contributions and / or persons who are currently completing their first degree or first professional qualification.
Please send registrations by e-mail to firstname.lastname@example.org up to one week before the start of the event. The number of external places is limited. A timely registration is recommended.
Anreise mit öffentlichen Verkehrsmitteln:
Vom Essener Hauptbahnhof gelangen Sie mit der Straßenbahnlinie 108 Richtung Bredeney oder der U-Bahn U11 Richtung Messe West-Süd/Gruga zur Haltestelle Rüttenscheider Stern. Von dort aus können sie entweder in die Straßenbahnlinie 101 Richtung Helenenstraße umsteigen, Ausstieg Zweigertstraße, oder vom Rüttenscheider Stern den kurzen Weg zum IMIBE zu Fuß zurücklegen. Das IMIBE befindet sich im Colonia Haus in der dritten Etage.
Anreise mit dem Auto:
Von Münster: Nehmen Sie die A43 in Richtung Recklinghausen/Dülmen. Bei der Ausfahrt 16 Bochum-Riemke wechseln Sie auf die B51 in Richtung Bochum-Riemke/Bochum-Hofstede/Herne-Zentrum. Halten Sie sich rechts und folgen Sie der B51 in Richtung Hattingen/Bochum-Zentrum. Nehmen Sie die A40 in Richtung Essen-Zentrum bis zur Ausfahrt 23 Essen-Zentrum. Von dort fahren Sie in Richtung Essen Zentrum/B224. Halten Sie sich links und fahren Sie auf die Kruppstraße. An der nächsten Kreuzung biegen Sie links in die Bismarckstraße ein. Nach etwa 1,5 km biegen Sie rechts in die Zweigertstraße ein. Das Colonia Haus befindet sich auf der linken Seite.
Von Köln: Nehmen Sie die A3 in Richtung Oberhausen bis zum Kreuz Breitscheid. Wechseln Sie auf die A52 in Richtung Essen und folgen Sie der Autobahn bis zur Ausfahrt 28 Essen-Rüttenscheid. Folgen Sie der Norbertstraße, ehe Sie links auf die Alfredstraße abbiegen. Nach etwa 800 m biegen Sie links in die Zweigertstraße ein. Das Colonia Haus befindet sich auf der linken Seite.
Von Dortmund: Nehmen Sie die A40 in Richtung Essen/Bochum bis zur Ausfahrt 23 Essen-Zentrum. Von dort fahren Sie in Richtung Essen Zentrum/B224. Halten Sie sich links und fahren Sie auf die Kruppstraße. An der nächsten Kreuzung biegen Sie links in die Bismarckstraße ein. Nach etwa 1,5 km biegen Sie rechts in die Zweigertstraße ein. Das Colonia Haus befindet sich auf der linken Seite.
Von Düsseldorf: Nehmen Sie die A44 in Richtung Velbert/Essen/Oberhausen/Flughafen Düsseldorf und wechseln Sie am Dreieck Düsseldorf Nord auf die A52 in Richtung Essen/Oberhausen. Nehmen Sie die Ausfahrt 28 Essen-Rüttenscheid und folgen Sie der Norbertstraße, ehe Sie links auf die Alfredstraße abbiegen. Nach etwa 800 m biegen Sie links in die Zweigertstraße ein. Das Colonia Haus befindet sich auf der linken Seite.
Leiter des PhD-Programms
Prof. Dr. med. Andreas Stang, MPH
Tel.: + 49 201/723-77-263
Institut für Medizinische Informatik, Biometrie und Epidemiologie (IMIBE)
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